Unimod, View record [
Accession #: 1000
]
| Accession # |
1000 |
PSI-MS Name |
|
Interim Name |
AHA-Alkyne |
| Description |
Azidohomoalanine (AHA) bound to propargylglycine-NH2 (alkyne) |
| Composition |
H(5) C(4) N(5) O S(-1) |
Monoisotopic |
107.077339 |
Average |
107.0504 |
| Site |
M |
Position |
Anywhere |
Classification |
Chemical derivative |
| Source |
Journal |
Reference |
Dieterich DC et al., (2007) Labelling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino acid tagging. Nature Protocols 2(3): 532-40 |
| Notes |
Methionine (C5H11NO2S) is substituted in culture with azidohomoalanine (AHA - C4H8N4O2). The azide group reacts with the alkyne group propargylglycine-NH2. As a result the side chain of methionine (C3H7S) is substituted by C7H12N5O. |
| Curator |
BThomas |
Last Modified |
2010-10-03 13:44:56 |
Verified |
No |
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