| Accession # |
1383 |
PSI-MS Name |
|
Interim Name |
PyridoxalPhosphateH2 |
| Description |
PLP bound to lysine reduced by sodium borohydride (NaBH4) to create amine linkage |
| Alt. Description |
Pyridoxal Phosphate reduced |
| Composition |
H(10) C(8) N O(5) P |
Monoisotopic |
231.029660 |
Average |
231.1425 |
| Site |
K |
Position |
Anywhere |
Classification |
Chemical derivative |
| Comment |
This is a chemical derivatization of the PLP imine with sodium borohydride to reduce imine bound through lysine epsilon amine group to chemical stable amine linkage |
| Source |
Other |
Reference |
We are currently trying to profile the PLP proteins of various bacteria and locate their binding sites using LC-MS of trypsin treated proteins. Under these condition the PLP imine is cleaved and therefore we need to reduce the imine bond to the chemical stable amine using sodium borohydride |
| Curator |
bphilmus |
Last Modified |
2013-05-03 17:30:38 |
Verified |
No |
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