Unimod, View record [
Accession #: 325
]
| Accession # |
325 |
PSI-MS Name |
FP-Biotin |
Interim Name |
FP-Biotin |
| Description |
10-ethoxyphosphinyl-N-(biotinamidopentyl)decanamide |
| Alt. Description |
O-ethyl-N-(biotinamidopentyl)decanamido phosphonate |
| Composition |
H(49) C(27) N(4) O(5) P S |
Monoisotopic |
572.316129 |
Average |
572.7405 |
| Site |
S |
Position |
Anywhere |
Classification |
Chemical derivative |
| Site |
Y |
Position |
Anywhere |
Classification |
Chemical derivative |
| Site |
T |
Position |
Anywhere |
Classification |
Chemical derivative |
| Site |
K |
Position |
Anywhere |
Classification |
Chemical derivative |
| Source |
Journal |
Reference |
Liu, Patricelli and Cravatt; Activity-based protein profiling: The serine hydrolases. Proc Natl Acad Sci USA 96, 14694-14699 (1999) |
| Source |
Journal |
Reference |
Schopfer, Champion, Tamblyn, Thompson and Lockridge; Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410). Anal Biochem 345, 122-132 (2005) |
| Source |
PubMed PMID |
Reference |
10611275 |
| Source |
Journal |
Reference |
Grigoryan, Li, Xue, Grigoryan, Schopfer and Lockridge; Mass spectral characterization of organophosphate-labeled lysine in peptides. Analytical Biochemistry 394, 92-100 (2009) |
| Notes |
FP-biotin was designed to label the active site serine of serine esterases/proteases. |
| Curator |
lmschopfer |
Last Modified |
2010-02-24 20:54:27 |
Verified |
No |
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