| Accession # |
887 |
PSI-MS Name |
|
Interim Name |
MDCC |
| Description |
covalent linkage of maleimidyl coumarin probe (Molecular Probes D-10253) |
| Alt. Description |
CAS 156571-46-9 |
| Alt. Description |
7-diethylamino-3-((((2-maleimidyl)ethyl)amino)carbonyl)coumarin |
| Composition |
H(21) C(20) N(3) O(5) |
Monoisotopic |
383.148121 |
Average |
383.3978 |
| Site |
C |
Position |
Anywhere |
Classification |
Chemical derivative |
| Comment |
Due to the mechanism of maleimidyl modification of Cys, the molecular weight of MDCC equals the mass shift created upon crossllinking (no chemical leaving group). During MS/MS, MDCC can reasonably be predicted to fragment readily and at various positions. |
| Source |
Other |
Reference |
technical resources at Molecular Probes |
| Notes |
MDCC is used extensively as a fluorescent probe to report changes in protein conformation. |
| Curator |
shartson |
Last Modified |
2008-12-05 09:32:22 |
Verified |
No |
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