Unimod, View record [ Accession #: 895 ]

Accession #	895		PSI-MS Name		Interim Name	Biotin-PEG-PRA
Description	Biotin polyethyleneoxide (n=3) alkyne
Composition	H(42) C(26) N(8) O(7)		Monoisotopic	578.317646	Average	578.6611
Specificity Definition 1
Site	M		Position	Anywhere	Classification	Chemical derivative
Notes and References
Source	Misc. URL	Reference	Page 12 Scheme 1: (1) Structure of azidohomoalanine (2) Biotin-PEO-alkyne in our case PEO n=3 as in this publication
Source	Journal	Reference	Drug Discovery Today Volume 8, Issue 24, 15 December 2003, Pages 1128-1137 Figure 4 page 1335
Notes	Methionine (C5H11NO2S) is substituted in cell culture by Azidohomoalanine (C4H8N4O2). The azido group reacts with an alkyne group attached to a linker (PEO) with a biotin group at the end (C27H45N5O7S). As a result the side chain of Met (C3H7S) is substitued by C29H49N8O7S.
Curator	Larsenmarsen	Last Modified	2009-02-06 16:50:56		Verified	No